Genetically Reduced Antioxidative Protection and Increased Ischemic Heart Disease Risk
نویسندگان
چکیده
منابع مشابه
Increased risk of ischemic heart disease among subjects with cataracts
BACKGROUND Association between cataract and the risk of ischemic heart disease (IHD) development is not completely clear. PURPOSE The primary aim of the study was to evaluate the association between cataract and the risk of incident IHD. The secondary aim was to investigate the subsequent IHD risk of patients with cataracts undergoing cataract surgery. METHODS Retrospective data from the Lo...
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background: coronary artery disease is recognized as one of the three major causes of mortality around the world. the role of inflammation in producing coronary artery disease has been established in previous studies. since periodontitis, which is highly prevalent, is considered as a cause of inflammation, its influence on producing coronary artery disease was investigated in the present study ...
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BACKGROUND Hyperglycemia-induced oxidative stress is one mechanism believed to underlie diabetic vascular disease. We tested the hypothesis that diabetic subjects heterozygous for extracellular superoxide dismutase (SOD3) R213G, which entails lower antioxidant capacity in tissues, have increased risk of cardiovascular disease and heart failure. METHODS We used the prospective Copenhagen Gener...
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چکیده مقدمه: بیماری های ایسکمیک قلب با ویژگی کاهش خون رسانی به ماهیچه قلب، به علت بیماری های عروق کرونر از جمله آترواسکلروز ایجاد می شود. از افزایش فعالیت گزانتین اکسیداز نیز منجر به عدم کارایی عروق در خون رسانی به عضله ی قلب و ایجاد انواع ایسکمی و آسیبهای بافتی و عروقی می شود. به نظر می رسد، داروهای مهارکننده گزانتین اکسیداز از طریق افزایش شرب بافتی در بهبود علائم بیماری های ایسکمیک قلب موثر ...
Genetically elevated apolipoprotein A-I, high-density lipoprotein cholesterol levels, and risk of ischemic heart disease.
CONTEXT Epidemiologically, levels of high-density lipoprotein (HDL) cholesterol and its major protein constituent, apolipoprotein A-I (apoA-I), are inversely related to risk of ischemic heart disease (IHD). OBJECTIVE We tested whether common genetic variation in the apolipoprotein A1 gene (APOA1) contributes to apoA-I and HDL cholesterol levels and risk of IHD in the general population. DES...
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ژورنال
عنوان ژورنال: Circulation
سال: 2004
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.0000105720.28086.6c